Ubudahangarwa bwa Mycobacterium Tuberculosis Rifampicin

Rifampicin yakoreshejwe cyane mu kuvura abarwayi ba gituntu cy’ibihaha kuva mu mpera za 1970, kandi igira ingaruka zikomeye. Ni yo mahitamo ya mbere yo kugabanya imiti ikoreshwa ku barwayi ba gituntu cy’ibihaha. Ubudahangarwa bwa Rifampicin buterwa ahanini n’impinduka mu ngirabuzimafatizo ya rpoB. Nubwo imiti mishya irwanya igituntu ihora isohoka, kandi ubushobozi bw’abarwayi ba gituntu cy’ibihaha nabwo bwakomeje kwiyongera, haracyari ibura ry’imiti irwanya igituntu, kandi ikoreshwa ry’imiti idahuje n’ubwenge mu buvuzi riri hejuru cyane. Birumvikana ko igituntu cya Mycobacterium mu barwayi ba gituntu cy’ibihaha kidashobora kwicwa burundu mu gihe, amaherezo biganisha ku ngero zitandukanye z’ubudahangarwa bw’imiti mu mubiri w’umurwayi, bikongera igihe cy’indwara, kandi byongera ibyago byo gupfa k’umurwayi. Iyi mashini ikwiriye mu gusuzuma ubwandu bwa Mycobacterium tuberculosis no kumenya igituntu cya rifampicin, ibi bikaba ingirakamaro mu gusobanukirwa ubudahangarwa bw’imiti ya mycobacterium tuberculosis yandujwe n’abarwayi, no gutanga uburyo bw’inyongera bwo kuyobora imiti.