Mycobacterium tuberculose acide na rifampicin (RIF), kurwanya (InH)

Mycobacterium igituntu acide na rifampicin (RIF), kurwanya (InH) ishusho igaragara

Ibisobanuro bigufi:

Ibi bikoresho bikoreshwa mubyerekeranye no kumenya neza Vitro , Kurwanya Rifampisitani kumenya akarere) ya RPOB Gene ya MycobaCherium igituntu rifampicin kurwanya, kimwe no mu ihinduka ry'imbuga nyamukuru za MycobaCerium ya Isonianium Kurwanya Ibinure bya Isonicice ya mycobacterium igituntu cyanduye na umurwayi.

Ohereza imeri kuri twe

Ibisobanuro birambuye

Ibicuruzwa

Izina ry'ibicuruzwa

HWTS-RT147 Mycobacterium Tuberculose acide na Rifampingi (RIF), (INH) Gutahura Kit (Gushonga umurongo)

Epidemiology

Mycobacterium igituntu, bidatinze nkadulls ya bacill^[1]. Ariko, kubera gukoresha nabi ibiyobyabwenge byo kurwanya ibinutu hamwe nibiranga urukuta rwa Mycobacterium, kandi ifishi ya MycobaCerium yacyo ubwayo, igituntu cya Mycobacterium, igituntu cya benshi mubituntu (MDR- Igituntu), kirwanya ibiyobyabwenge bibiri bisanzwe kandi bifite akamaro, rifampicin na isoniyaID^[2].

Ikibazo cyo kurwanya ibiyobyabwenge ibiyobyabwenge kibaho mubihugu byose byabajijwe nande. Kugirango dushe gahunda zubuvuzi zukuri kubarwayi ba Tuberculose, birakenewe kubona ibiyobyabwenge byo kurwanya ibinutu, cyane cyane rifampiricique, bikaba byarabaye intandaro yo gusuzuma yasabwa na ba^[3]. Nubwo kuvumburwa kwa Rifampicine bihwanye nubuvumbuzi bwa MDR-TB, kumenya gusa ingwate za Rifampicine zirengagiza IH (Kuvuga RIFAMPINIC) na Mono-irwanya Isoniazid ariko irwanya Rifampicin), zishobora gutuma abarwayi bakorerwa intangiriro zidafite ishingiro Ubuvuzi. Kubwibyo, ibizamini bya Isoniyadid na Rifampisitani Kurwanya Nibisabwa byibuze bikenewe muri gahunda zose za Dr-TB^[⁴^].

Tekinike

Ububiko	≤-18 ℃
Imibereho-Ubuzima	Amezi 12
Ubwoko bw'ikigereranyo	Urugero rwa Sputum, Umuco ukomeye (LJ Hagati), Umuco wa Liquid (MGIT)
CV	<5.0%
Lod	Uguto tw'ibikoresho byo kumenya igituntu mycobacterium ni bagiteri 10 / ml;Uguto tw'ibikoresho kugirango utangire ubwoko bwishyamba bwumusozi nubwoko bwa mutant ni 150 bagiteri / ml; Imyenda y'ibikoresho yo gutahura ubwoko bwo mu gasozi bwa Isoniazid n'ubwoko bwa Mutant ni 200 bacteri / ml.
Umwihariko	1) Nta myitwarire yambukiranya mugihe ukoresheje ibikoresho kugirango umenye ADN wabantu ba Genomic (500ng), ubundi bwoko bwamahuru 28 ya mypobacteria, na Ubwoko bwa MycobaCacteria 4).2) Nta myitwarire yambukiranya mugihe ukoresheje ibikoresho kugirango umenye aho dutation yibindi gence zirwanya ibiyobyabwenge na isoniazirium byunvikana. Nkuko bigaragara mu mbonerahamwe ya 4).3) Ibintu bisanzwe bibangamiye mubyitegererezo bizageragezwa, nka Rifampicin (9mg / l), 12mg / l), oxymezoline (1mg / l), Mupirocin (20mg / l), Pyrazinamide (45mg / L), Zanamivir .
Ibikoresho bisabwa	Slan-96p Sisitemu NYAKURI PCR (Tekinoroji yubuvuzi Cology Co, Ltd.), Biorad CFX96 Igihe cya PCR