Kras 8 Mutation

INGINGO ZA KRAS Muri Gene yabantu, hafi 17% ~ 25% Igipimo cyigitugu Abarwayi ba Kanseri, 20% ~ 50 abarwayi. Kuberako poroteyine ya P21 yashyizweho na G-Ras iherereye hasi yinzira yamashusho, nyuma yinzira ya K-Raswm kwibeshaho nabi bya selile. Guhinduka muri rusange muri rusange muri rusange hatangaho kurwanya Egrosine Kibititurs mu barwayi ba kanseri y'ibihaha no guhangana na anti-egfr bantibound barwaye kanseri ya kanseri. In 2008, the National Comprehensive Cancer Network (NCCN) issued a clinical practice guideline for colorectal cancer, which pointed out that the mutation sites that cause K-ras to be activated are mainly located in codons 12 and 13 of exon 2, and recommended that Abarwayi bose bafite kanseri ya marike ya marike ya metastike barashobora kwipimisha K-Ras mbere yo kuvurwa. Kubwibyo, byihuse kandi neza gutahura kwa K-Ras Gen Rutation bifite akamaro gakomeye mubuyobozi bwa kavukire. Ibi bikoresho bikoresha ADN nkicyitegererezo kugirango utange isuzuma ryimiterere ya gutemamubiri, rishobora gufasha kanseri yibihaha hamwe nabandi barwayi b'ibibyingukirwa nibiyobyabwenge. Ibizamini byikizamini bya Kit ni ibyuma gusa kandi ntibigomba gukoreshwa nkishingiro ryonyine ryo kuvura abantu kugiti cyabo. Abaganga bagomba guca imanza byuzuye kubisubizo byikizamini bishingiye kubintu nkuko umurwayi ameze, ibimenyetso byabayobyabwenge, igisubizo cyo kuvura nibindi bipima bya laboratoire.