Umuntu TEL-AML1 Fusion Gene Mutation
Izina ryibicuruzwa
HWTS-TM016 Umuntu TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Epidemiologiya
Indwara ya lymphoblastique ikaze (BYOSE) ni indwara mbi ikunze kugaragara mu bwana. Mu myaka yashize, leukemia ikaze (AL) yahindutse kuva mubwoko bwa MIC (morphologie, immunology, cytogenetics) ihinduka ubwoko bwa MICM (hiyongereyeho ibizamini bya biologiya). Mu 1994, byavumbuwe ko guhuza TEL mu bwana byatewe no guhinduranya chromosomal idasanzwe t (12; 21) (p13; q22) muri B-lineage acute lymphoblastique leukemia (BYOSE). Kuva havumburwa gene ya AML1, gene ya TEL-AML1 ninzira nziza yo guca imanza zabana bafite indwara ya lymphoblastique ikaze.
Umuyoboro
| FAM | TEL-AML1 fusion gene |
| ROX | Igenzura ryimbere |
Ibipimo bya tekiniki
| Ububiko | ≤-18 ℃ |
| Ubuzima bwa Shelf | Amezi 9 |
| Ubwoko bw'icyitegererezo | icyitegererezo cy'amagufwa |
| Ct | ≤40 |
| CV | <5.0% |
| LoD | 1000Copi / mL |
| Umwihariko | Nta re-reaction iri hagati yibikoresho nizindi genes zo guhuza nka BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, PML-RARa fusion genes. |
| Ibikoresho bikoreshwa | Ikoreshwa rya Biosystems 7500 Sisitemu-Igihe nyacyo PCR Ikoreshwa rya Biosystems 7500 Byihuse-Igihe-Sisitemu ya PCR QuantStudio®5 Sisitemu-Igihe nyacyo PCR SLAN-96P Sisitemu nyayo-PCR LightCycler®480 Sisitemu nyayo-PCR LineGene 9600 Yongeyeho Sisitemu-Igihe Cyuzuye PCR MA-6000-Igihe-Cyuzuye Cyumubare Wubushyuhe BioRad CFX96 Sisitemu-Igihe Cyuzuye PCR BioRad CFX Opus 96 Sisitemu Yigihe-PCR |
Urujya n'uruza rw'akazi
RNAprep Amaraso Yuzuye Igikoresho cyo gukuramo RNA (DP433).
