Impinduka mu mikorere ya TEL-AML1 y'abantu mu bijyanye na Gene
Izina ry'igicuruzwa
HWTS-TM016 Human TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Ubumenyi bw'indwara
Leukemia y'urumogi itera kanseri (ALL) ni yo ndwara ikunze kugaragara cyane mu bwana. Mu myaka ya vuba aha, leukemia y'urumogi itera kanseri (AL) yahindutse kuva ku bwoko bwa MIC (imiterere, ubudahangarwa bw'umubiri, cytogenetics) ijya ku bwoko bwa MICM (inyongera ku isuzuma rya molekile). Mu 1994, byagaragaye ko TEL fusion mu bwana yaterwaga nonrandom chromosome translocation t(12;21)(p13;q22) muri B-lineage acute lymphoblastic leukemia (ALL) yavumbuwe. Kuva aho havumburiwe AML1 fusion gene, TEL-AML1 fusion gene ni bwo buryo bwiza bwo gusuzuma imiterere y'abana bafite leukemia y'urumogi itera kanseri.
Umuyoboro
| FAM | Ingirabuzimafatizo za TEL-AML1 |
| ROX | Igenzura ry'imbere |
Ibipimo bya tekiniki
| Ububiko | ≤-18℃ |
| Igihe cyo kumara | Amezi 9 |
| Ubwoko bw'ingero | icyitegererezo cy'umusemburo w'amagufwa |
| Ct | ≤40 |
| CV | <5.0% |
| LoD | Kopi 1000/mL |
| Ubwihariye | Nta guhuza hagati y’uturemangingo n’utundi turemangingo nka BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, PML-RARa. |
| Ibikoresho Bikoreshwa | Sisitemu za PCR zikoreshwa mu gihe nyacyo 7500 Sisitemu za PCR zikoreshwa mu buryo bwihuse 7500 Sisitemu za PCR za QuantStudio®5 mu gihe nyacyo Sisitemu za PCR za SLAN-96P mu gihe nyacyo Sisitemu ya LightCycler®480 Real-Time PCR Sisitemu yo Gusuzuma PCR ya LineGene 9600 Plus mu gihe nyacyo MA-6000 Umuvuduko w'ubushyuhe mu gihe nyacyo Sisitemu ya BioRad CFX96 ya PCR mu gihe nyacyo Sisitemu ya BioRad CFX Opus 96 ya PCR mu gihe nyacyo |
Urugendo rw'akazi
RNAprep Pure Blood Total RNA Extraction Kit (DP433).
