Antijeni B27 y'ingirabuzimafatizo z'amaraso mu mubiri w'umuntu
Izina ry'igicuruzwa
HWTS-GE011A-Igikoresho cyo Gupima Aside ya Nucleic ya Leukocyte y'Umuntu (PCR ya Fluorescence)
Ubumenyi bw'indwara
Ankylosing spondylitis (AS) ni indwara idakira itera ububabare ikwirakwira cyane cyane mu ruti rw'umugongo kandi ishobora no gufata ingingo za sacroiliac n'izindi ngingo ku rugero rutandukanye. Byagaragaye ko AS igaragaza ubwiyongere bw'imiryango kandi ifitanye isano rya hafi na antigen ya leukocyte y'umuntu HLA-B27. Ku bantu, ubwoko burenga 70 bwa HLA-B27 bwavumbuwe kandi bwaramenyekanye, muri bwo, HLA-B*2702, HLA-B*2704 na HLA-B*2705 ni zo ndwara zikunze kugaragara cyane. Mu Bushinwa, Singapuru, Ubuyapani n'akarere ka Tayiwani mu Bushinwa, ubwoko bukunze kugaragara bwa HLA-B27 ni HLA-B*2704, bungana na 54%, bugakurikirwa na HLA-B*2705, bungana na 41%. Iyi kit ishobora kubona ADN mu byiciro bya HLA-B*2702, HLA-B*2704 na HLA-B*2705, ariko ntabwo ibitandukanya.
Umuyoboro
| FAM | HLA-B27 |
| VIC/HEX | Igenzura ry'imbere |
Ibipimo bya tekiniki
| Ububiko | Amazi: ≤-18℃ Mu mwijima |
| Igihe cyo kumara | Amazi: Amezi 18 |
| Ubwoko bw'ingero | ingero z'amaraso yose |
| Ct | ≤40 |
| CV | ≤5.0% |
| LoD | 1ng/μL |
| Ubwihariye
| Ibisubizo by'ibizamini byabonetse muri aka gakoresho ntibizakorwaho na hemoglobine (<800g/L), bilirubini (<700μmol/L), na lipide mu maraso/triglycerides (<7mmol/L) mu maraso. |
| Ibikoresho Bikoreshwa | Sisitemu za PCR zikoreshwa mu gihe nyacyo 7500 Sisitemu za Biosystems zikoreshwa StepOne Real-Time PCR Systems Sisitemu ya LightCycler®480 Real-Time PCR Sisitemu ya Agilent-Stratagene Mx3000P Q-PCR |
