Umuntu BCR-ABL Fusion Gen Mutation
Izina ry'ibicuruzwa
Hwts-Ge010A-Umuntu BCR-ABL Fusion Gen Mutation Gutahura Kit (Fluorescence PCR)
Hwts-ge016a-guhagarika-yumiwe-yumye
Epidemiology
MyelognoukeleukeRike (cml) ni indwara mbi ya clonal ya selile za bematopoiics. Abarwayi barenga 95% bitwara Chrodelphia (PH) muri selile zabo. Preditant Pethogenezi ya CML ni izi zikurikira: Gene ya BCR-ABL yashinzwe no kwimuka hagati ya Abl Proto-oncogene (Abelson Murine leukemia viruke Bcr) gene ku kuboko kurambuye bya chromosome 22 (22q11); Poroteyine ya Fusion yashyizweho na gene ifite ibikorwa bya Tyrosine kinase (tk), kandi ikora inzira yamakuru yayo (nka jas, na jak, na jak / jak / jak / jak / jak / jak / jak kubaho kwa CML. BCR-ABL nimwe mubipimo byingenzi bya CML. Guhindura imbaraga zurwego rwinyandiko nicyerekezo cyizewe cyo guca urubanza rwa prognostic ya leukemia kandi birashobora gukoreshwa muguhakana ibitambo bya leukemia nyuma yo kuvurwa.
Umuyoboro
| Umuryango | BCR-ABL Fusion |
| Vic / Hex | Kugenzura imbere |
Tekinike
| Ububiko | Amazi: ≤-18 ℃ mu mwijima |
| Imibereho-Ubuzima | Amazi: amezi 9 |
| Ubwoko bw'ikigereranyo | Amagufwa |
| Lod | Amakopi 1000 / ML |
| Umwihariko
| Nta musaraba-ugendana hamwe n'ibindi bipimo bya Gereza ya Fusion,, E2A-PBX1, Mll-AM4, AML1-RORA, na PMR |
| Ibikoresho bisabwa | Gushyira mu bikorwa biosystems 7500 igihe cya sisitemu ya PCR Gushyira mu bikorwa biosystems 7500 byihuse-sisitemu ya PCR Quartudio® 5 igihe-nyacyo PCR sisitemu Scan-96p sisitemu nyayo pcr sisitemu Umucyo®480 Igihe Cyigihe cya PCR Linegene 9600 wongeyeho sisitemu yigihe cya PCR Ma-6000 nyayo-nyayo Biorad CFX96 Igihe cya PCR Biorad CFX OPUS 96 Igihe cya PCR |
