PCT / IL-6 Byahujwe

PCT ibanziriza calcitonine, ni glycoproteine ​​igizwe na acide 116 amine.Umubare wa molekile ni 12.8kd.Ntabwo ikora ibikorwa bya hormone.Mugihe cyimiterere yumubiri, PCT ikomatanyirizwa kandi ikarekurwa na selile ya tiroyide C.Mugihe cyo kwandura bagiteri, macrophage na monocytes mu mwijima, lymphocytes na selile endocrine mu bihaha no mu mara yo mu nda bihuza kandi bigasohora PCT nyinshi bitewe na endotoxine, ikibyimba cya nekrosis-α na interleukin-6, bigatuma ubwiyongere bugaragara muri serumu PCT urwego.
Interleukin-6 ni cytokine igaragazwa nubudahangarwa bw'umubiri mugihe cyo gukomeretsa no kwandura.Ikorwa na fibroblast, monocytes / macrophage, T lymphocytes T, lymphocytes B, selile epithelale, keratinocytes, na selile zitandukanye.IL-6 igizwe n'iminyururu ibiri ya glycoproteine, imwe ni α urunigi rufite uburemere bwa 80kd;ikindi ni β urunigi rufite uburemere bwa 130kd [5].Niba umubiri wumuntu uterwa no gutwikwa, urwego rwa IL-6 ruzamuka vuba, ari nako ruhuza ibyiciro bikaze byumwijima kandi bigatera imbere kubyara poroteyine zikomeye nka C-reaction proteine ​​(CRP) na serumu amyloide A (SAA) ).Kubwibyo, IL-6 nikimenyetso cyambere cyo kuzamuka mugihe habaye umuriro.