Gicurasi 17, 2023 ni umunsi wa 19 hypercenance ".
Hypertension azwi nka "umwicanyi" mubuzima bwabantu. Abarenga kimwe cya kabiri cy'indwara z'umutima, inkoni no gutsindwa n'umutima biterwa n'imbuto. Kubwibyo, turacyafite inzira ndende yo kujya gukumira no kuvura hypertension.
01 Icyubahiro Cyiza cya HyperSension
Kw'isi yose, abantu bagera kuri miliyari 1.28 bakuze bafite imyaka 30-79 barwaye umuvuduko ukabije w'amaraso. 42% gusa by'abarwayi bafite hypertension barafatwa kandi bakavurwa, kandi umwe mu barwayi batanu bafite hypertension yabo. Muri 2019, umubare w'abantu bapfa batewe n'isi ku isi hose barenze miliyoni 10, ibarura igera kuri 19% by'impfu zose.
02 Hypertension ni iki?
Hypertension ni syndrome yubuvuzi irangwa no kwiyongera k'umuvuduko wamaraso mubikoresho bya arterial.
Abarwayi benshi nta bimenyetso bigaragara cyangwa ibimenyetso bigaragara. Umubare muto w'abarwayi ba hypertel barashobora kuzunguruka, umunaniro cyangwa imbeba. Bamwe mu barwayi bafite umuvuduko wamaraso ya systolic wo muri 200mmhg cyangwa hejuru ntibashobora kuba bafite ubuvuzi bugaragara, ariko umutima wabo, ubwonko, impyiko, imiyoboro y'amaraso byangiritse ku rugero runaka. Mugihe indwara igenda itera imbere, indwara zibangamiye ubuzima nko kunanirwa kwumutima, kunanirwa kwa Myocardial, kuva amaraso mu bwonko, kudashoboka, Uremia, na periphery ocluction izabaho.
. Birashobora kuba bifitanye isano nibintu byinshi nkibipimo, imibereho, umubyibuho ukabije, guhangayika n'imyaka.
. Birayongereye umuvuduko wamaraso uterwa nizindi ndwara cyangwa ibiyobyabwenge, nkindwara yimpyiko, indwara yimitima, indwara z'umutima, ingaruka zibyibuto, nibindi.
03 Kuvura ibiyobyabwenge kubarwayi ba hyperte ihenze
Amahame yo kuvura hypersension ni: gufata imiti igihe kirekire, agenga ibimenyetso byumuvuduko wamaraso, kunoza ibimenyetso, gukumira ibibazo, ibinyamakuru byihariye byo guteza imbere imitima, muri ibyo Gukoresha igihe kirekire imiti ya antihyperteng ni igipimo gikomeye cyo kuvura.
Ubusanzwe abaganga bahitamo guhuza ibiyobyabwenge bitandukanye ukurikije urwego rwumuvuduko wamaraso hamwe nindwara yumutima rusange wumurwayi, kandi ihuza imiti yibiyobyabwenge kugirango igere ku kuyobora umuvuduko mwiza wamaraso. Ibiyobyabwenge bya antiryperteng bikunze gukoreshwa nabarwayi birimo angiotensin-guhindura enzyme ibibuza (angiotensin reseptor baterneris (ARIOI), β-baternal, umuyoboro wa Calcium (CCB), na baltitics.
04 Gupima genetike kubiyobyabwenge byihariye kubarwayi ba hyperte ihenze
Kugeza ubu, ibiyobyabwenge bigabanya ubukana byakoreshejwe mumyitozo y'amavuriro muri rusange bifite itandukaniro ku muntu, kandi ingaruka zo gukiza ibiyobyabwenge bya hypertension birafitanye isano cyane na Polymorphiism. Farumacomics irashobora gusobanura isano iri hagati yibikorwa byihariye kubiyobyabwenge no gutandukana kwa genetike, nkingaruka zo gukiza, urwego rwa dosiye hamwe nibitekerezo bibi birategereje. Abaganga bagaragaza ko intego za Gene zigira uruhare mu mabwiriza y'umuvuduko w'amaraso mu barwayi barashobora gufasha kugena imiti.
Kubwibyo, kumenya ibiyobyabwenge bifitanye isano nibiyobyabwenge birashobora gutanga ibimenyetso bifatika byo guhitamo amashanyarazi nuburyo bwibiyobyabwenge, no kunoza umutekano nuburyo bwo gukoresha ibiyobyabwenge.
05 abaturage bakurikizwa kubizamini bya genetike yimiti yihariye ya hypertension
(1) abarwayi bafite hypertension
(2) Abantu bafite amateka yumuryango wa hypertension
(3) Abantu bagize ibyago bibi
(4) Abantu bafite ingaruka mbi zo kuvura ibiyobyabwenge
(5) Abantu bakeneye gufata ibiyobyabwenge byinshi icyarimwe
06 ibisubizo
Macro & Micro-Ikizamini cyateguye ibibutsi byinshi kubyerekeranye no kumenya imiti ya hypertension, gutanga igisubizo rusange kandi cyuzuye cyo kuyobora imiti yumuriro no gusuzuma ingaruka zibiyobyabwenge bibi:
Ibicuruzwa birashobora kumenya 8 gene loci bijyanye nimiti ya antihypertel hamwe namasomo 5 yingenzi yibiyobyabwenge (B AdrenenGic yandika Enzyme Antagoniste, Adiotensin Ii Reseptor, Adiotensin II no gusuzuma ibyago byo gutekereza nabi. Mu kumenya imiti igabanya ibiyobyabwenge n'ibiyobyabwenge, abaganga barashobora kuyoborwa kugirango bahitemo ibiyobyabwenge bikwiye no gutanga ibiyobyabwenge byihariye, kandi banoza imikorere n'umutekano w'ubuvuzi bwa antiry
Byoroshye gukoresha: Gukoresha tekinoroji yo hagati, amayeri 2 yimyitwarire arashobora kubona imbuga 8.
Ubushishozi bwo hejuru: Imipaka ntarengwa yo gutahura ni 10.0ng / μl.
Ukuri: Ingero 60 zose zageragejwe, kandi imbuga za SNP za buri gene zahuza n'ibisekuru bya gisekuru cyangwa igisekuru cya mbere, kandi igipimo cyo kumenya, kandi igipimo cyo gutsinda cyari 100%.
Ibisubizo byizewe: Igenzura ryimbere ryimbere rirashobora gukurikirana inzira yose yo gutahura.
Igihe cya nyuma: Gicurasi-17-2023