Igitekerezo cy'ikibyimba
Ikibyimba ni ikinyabuzima gishya cyaremwe no kwiyongera kudasanzwe kw'uturemangingo mu mubiri, akenshi kigaragara nk'ikibyimba kidasanzwe mu gice cy'umubiri cyo hafi aho. Kuvuka kwa ikibyimba ni ingaruka z'ihungabana rikomeye mu mikurire y'uturemangingo bitewe n'ibintu bitandukanye bitera kanseri. Kuvuka kudasanzwe kw'uturemangingo biganisha ku kuvuka kwa kanseri byitwa kwiyongera kwa neoplastic.
Mu 2019, Cancer Cell yasohoye inkuru vuba aha. Abashakashatsi bavumbuye ko metformin ishobora kubuza cyane gukura kwa kanseri mu gihe umuntu yiyiriza ubusa, kandi bavuze ko inzira ya PP2A-GSK3β-MCL-1 ishobora kuba intego nshya yo kuvura kanseri.
Itandukaniro rikomeye riri hagati y'ikibyimba kitari kibi n'ikibyimba kibi
Ikibyimba kitari cyiza: gukura buhoro, kapsule, kubyimba, kunyerera ukozeho, imbibi zisobanutse neza, nta kumera neza kw'indwara, ibimenyetso byo gukandagira mu gace runaka, muri rusange nta mubiri wose, akenshi ntibitera urupfu rw'abarwayi.
Kanseri mbi: gukura vuba, gukura cyane, gufatana n'ingingo zikikije, kudashobora kugenda iyo umuntu abikozeho, imbibi zidasobanutse neza, kwangirika byoroshye, kongera kugaragara nyuma yo kuvurwa, umuriro muke, kudashaka kurya mu ntangiriro, kugabanya ibiro, kubura amaraso menshi, kubura amaraso n'umuriro mu gihe cya nyuma, nibindi. Iyo idavuwe ku gihe, akenshi itera urupfu.
"Kubera ko ibibyimba bidakomeye n'ibibyimba bibi bitagaragaza ibimenyetso bitandukanye gusa, ahubwo ikiruta byose ni uko imiterere yabyo itandukanye, bityo rero iyo umaze kubona ikibyimba mu mubiri wawe n'ibimenyetso byavuzwe haruguru, ugomba gushaka inama kwa muganga ku gihe."
Uburyo bwo kuvura ikibyimba ku giti cyabwo
Umushinga wa Genome y'Abantu n'Umushinga Mpuzamahanga wa Genome ya Kanseri
Umushinga wa Human Genome Project, watangijwe ku mugaragaro muri Leta Zunze Ubumwe za Amerika mu 1990, ugamije gufungura kode zose z’uturemangingo zigera ku 100.000 mu mubiri w’umuntu no gukurura ubwoko bw’uturemangingo tw’abantu.
Mu 2006, Umushinga Mpuzamahanga wa Genome ya Kanseri, watangijwe ku bufatanye n'ibihugu byinshi, ni ubundi bushakashatsi bukomeye bwa siyansi nyuma y'Umushinga wa Genome y'Abantu.
Ibibazo by'ingenzi mu kuvura kanseri
Gusuzuma no kuvura ku giti cye = Gusuzuma ku giti cye + imiti igamije
Ku barwayi benshi barwaye indwara imwe, uburyo bwo kuvura ni ugukoresha umuti umwe n'igipimo gisanzwe, ariko mu by'ukuri, abarwayi batandukanye bafite itandukaniro rikomeye mu ngaruka zo kuvura n'ingaruka mbi, kandi rimwe na rimwe iri tandukaniro rishobora no kwica.
Uburyo bwo kuvura hifashishijwe imiti yihariye bufite imiterere yo kwica uturemangingo tw’ikibyimba mu buryo bwihariye butica cyangwa bwangiza uturemangingo dusanzwe gake cyane, kandi ingaruka mbi nke zigatuma abarwayi bagira ubuzima bwiza n’ingaruka nziza ku buvuzi bwabo.
Kubera ko uburyo bwo kuvura bugamije kwibasira ingirabuzimafatizo runaka, ni ngombwa kumenya uturemangingo tw’ikibyimba no kumenya niba abarwayi bafite utwo bagamije mbere yo gufata imiti, kugira ngo bigire ingaruka nziza ku kuvura.
Gusuzuma imiterere y'uturemangingo tw'ikibyimba
Gusuzuma gene ya kanseri ni uburyo bwo gusesengura no gukurikirana ADN/RNA y'uturemangingo twa kanseri.
Akamaro ko gupima utunyangingo tw’ikibyimba ni ukuyobora uburyo bwo guhitamo imiti ikoreshwa mu kuvura (imiti igamije, imiti igabanya ubukana bw’umubiri n’indi miti mishya ya SIDA, uburyo bwo kuyivura nyuma y’igihe gito), no kumenya igihe bizabera n’igihe bizasubira.
Ibisubizo byatanzwe na Acer Macro na Micro-Test
Igikoresho cyo Gusuzuma Impinduka za Gene 29 z'Umuntu (Fluorescence PCR))
Ikoreshwa mu gupima ihinduka ry’imiterere ry’uturemangingo dusanzwe muri exon 18-21 ya EGFR gene mu barwayi ba kanseri y’ibihaha batari abarwayi b’uturemangingo duto muri laboratoire.
1. Gushyiraho uburyo bwo kugenzura ubuziranenge bw'imbere muri sisitemu bishobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.
2. Ububasha bwo kwiyumvamo cyane: igipimo cy’impinduka cya 1% gishobora kugaragara neza inyuma y’umuti wa aside nucleic reaction wa 3ng/μL wild-type.
3. Ubwinshi buhanitse: nta buryo bwo guhuza ibisubizo bya ADN y’uturemangingo tw’umubiri w’umuntu n’ubundi bwoko bw’ibinyabuzima byahinduwe.
KRAS 8 Mutations Detection Kit (Fluorescence PCR)
Ubwoko umunani bw'impinduka muri kodoni 12 na 13 za gene ya K-ras zikoreshwa mu gupima ADN ikuwe mu bice by'indwara bya parafini y'umuntu muri vitro.
1. Gushyiraho uburyo bwo kugenzura ubuziranenge bw'imbere muri sisitemu bishobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.
2. Ububasha bwo kwiyumvamo cyane: igipimo cy’impinduka cya 1% gishobora kugaragara neza inyuma y’umuti wa aside nucleic reaction wa 3ng/μL wild-type.
3. Ubwinshi buhanitse: nta buryo bwo guhuza ibisubizo bya ADN y’uturemangingo tw’umubiri w’umuntu n’ubundi bwoko bw’ibinyabuzima byahinduwe.
Kit yo Gusuzuma Impinduka za Gene ya ROS1 y'Umuntu (Fluorescence PCR)
Yakoreshejwe mu gupima ubwoko 14 bw'impinduka za ROS1 mu ngirabuzimafatizo mu barwayi ba kanseri y'ibihaha batari abarwayi bato mu buryo bwa vitro.
1. Gushyiraho uburyo bwo kugenzura ubuziranenge bw'imbere muri sisitemu bishobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.
2. Ubuhanga bwo hejuru: kopi 20 za fusion mutation.
3. Ubwinshi buhanitse: nta buryo bwo guhuza ibisubizo bya ADN y’uturemangingo tw’umubiri w’umuntu n’ubundi bwoko bw’ibinyabuzima byahinduwe.
Kit yo Gusuzuma Impinduka za Gene mu Mutation ya Human EML4-ALK (Fluorescence PCR)
Byakoreshejwe mu gupima ubwoko 12 bw'impinduka za EML4-ALK mu barwayi ba kanseri y'ibihaha batari abarwayi b'uturemangingo duto mu buryo bw'ikoranabuhanga.
1. Gushyiraho uburyo bwo kugenzura ubuziranenge bw'imbere muri sisitemu bishobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.
2. Ubuhanga bwo hejuru: kopi 20 za fusion mutation.
3. Ubwinshi buhanitse: nta buryo bwo guhuza ibisubizo bya ADN y’uturemangingo tw’umubiri w’umuntu n’ubundi bwoko bw’ibinyabuzima byahinduwe.
Kit yo Gusuzuma Impinduka mu Binyabuzima ya BRAF Gene V600E (Fluorescence PCR)
Ikoreshwa mu gupima mu buryo bw'imiterere impinduka za gene ya BRAF V600E mu bice by'umubiri bya melanoma y'umuntu, kanseri y'inkondo y'umura, kanseri ya tiroyide na kanseri y'ibihaha muri vitro.
1. Gushyiraho uburyo bwo kugenzura ubuziranenge bw'imbere muri sisitemu bishobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.
2. Ububasha bwo kwiyumvamo cyane: igipimo cy’impinduka cya 1% gishobora kugaragara neza inyuma y’umuti wa aside nucleic reaction wa 3ng/μL wild-type.
3. Ubwinshi buhanitse: nta buryo bwo guhuza ibisubizo bya ADN y’uturemangingo tw’umubiri w’umuntu n’ubundi bwoko bw’ibinyabuzima byahinduwe.
| Umubare w'Igikoresho | Izina ry'igicuruzwa | Ibisobanuro |
| HWTS-TM006 | Kit yo Gusuzuma Impinduka za Gene mu Mutation ya Human EML4-ALK (Fluorescence PCR) | Ibipimo 20 ku gikoresho Ibipimo 50 ku gikoresho |
| HWTS-TM007 | Kit yo Gusuzuma Impinduka mu Binyabuzima ya BRAF Gene V600E (Fluorescence PCR) | Ibizamini 24/agasanduku Ibipimo 48/agasanduku |
| HWTS-TM009 | Kit yo Gusuzuma Impinduka za Gene ya ROS1 y'Umuntu (Fluorescence PCR) | Ibipimo 20 ku gikoresho Ibipimo 50 ku gikoresho |
| HWTS-TM012 | Igikoresho cyo Gusuzuma Impinduka za Gene 29 z'Umuntu (Fluorescence PCR)) | Ibipimo 16/agasanduku Ibizamini 32/agasanduku |
| HWTS-TM014 | KRAS 8 Mutations Detection Kit (Fluorescence PCR) | Ibizamini 24/agasanduku Ibipimo 48/agasanduku |
| HWTS-TM016 | Kit yo Gusuzuma Impinduka za Gene za TEL-AML1 zo mu Mutwe w'Umuntu (Fluorescence PCR) | Ibizamini 24/agasanduku |
| HWTS-GE010 | Kit yo Gusuzuma Impinduka za Gene ya BCR-ABL (Fluorescence PCR) y'umuntu | Ibizamini 24/agasanduku |
Igihe cyo kohereza ubutumwa: 17 Mata 2024