Covid-19 (2019-NCOV) Yateye miliyoni amagana n'imiryango yabarirwa muri za miriyoni kuva yatontokwa mu mpera za 2019, bituma bigira ibihe byihutirwa ku isi. Ishami ry'Umuryango w'Abibumbye ryita ku Buzima (NINDE) RIKURIKIRA "MUTATO KUBONA"[1], ni ukuvuga Alpha, Beta, Gmama, Delta na Omirron, na Omirron Mutant Mutant Strain yorezo ku isi. Nyuma yo kwandura Omirron mutant, ibimenyetso biratonda, ariko kubantu badasanzwe nkindwara zidangora, ibyago byo kurwara bikomeye cyangwa urupfu nyuma yo kwandura bikiri hejuru. Urubanza ruhirata ku rubanza rwa Mutant muri Omicron, Amakuru Yisi Yukuri yerekana ko igipimo cyigihe cya mugitondo kigera kuri 0.75%, ni ikigereranyo cy'ibicurane Kera, irenga 10%, bigera hafi inshuro 100 za ibicurane bisanzwe[2]. Ibitekerezo bikunze kugaragara byo kwandura ni umuriro, inkorora, umuhogo, ufite umuhogo, myalgia, na millegia, nibindi.
Hariho ubwoko bune bwa virusi zibicurane: A, B, B, C na D. Ubwoko bw'ikinyabuzima nyamukuru burakomeye a (H1N1) na H3N2, na Strain na Yamagata). Ibicurane byatewe na virusi y'ibihe bibi bizatera icyorezo cy'igihembwe ndetse n'icyo gihe kidateganijwe buri mwaka, hamwe n'igipimo kinini. Dukurikije imibare, imanza zigera kuri miliyoni 3.4 zivurwa indwara z'ibicurane buri mwaka[3], kandi abantu bagera kuri 88.100 b'indwara z'ibicurane zishingiye ku rupfu, ibaruramari ku bantu 8.2% zipfuka[4]. Ibimenyetso by'amavuriro birimo umuriro, kubabara umutwe, miyalgia no gukorora. Amatsinda yibasiye amasoko menshi, nk'abagore batwite, impinja, abasaza n'abarwayi bafite indwara zidakira, bakunze kurwana n'ibindi bibazo, bishobora kuganisha ku rupfu mu manza zikomeye.
1 Covid-19 hamwe n'ingaruka z'ibicurane.
Gufatanya ibicurane hamwe na Covid-19 birashobora kongera ingaruka z'indwara. Ubushakashatsi bw'Abongereza bwerekana ko[5]Ugereranije na Coviction ya Covid-19 yonyine, ibyago byo guhumeka kw'imashini no kwandura ibitaro mu bitaro byiyongera kuri Covid-19 hamwe na virusi y'ibicurane byiyongereyeho 4.14 inshuro 2.35.
Ishuri Rikuru ry'ubuvuzi rya Tongji rya kaminuza ya Huazhong ya Ubumenyi n'ikoranabuhanga ryasohoye[6], birimo ubushakashatsi 95 burimo abarwayi 62,107 i Covid-19. Igipimo cy'amakuba ya virusi ya greenza cyanduye ni 2.45%, muri ibyo ibicurane bigize uruhare rugereranijwe. Ugereranije n'abarwayi banduye gusa Covid gusa - 19, abarwayi banduye ibicurane, abafite ibyago byinshi byo kugorana cyane, harimo no kwinjira mu ntera n'urupfu. Nubwo ubwinshi bwanduye ari buke, abarwayi bafite amasezerano bahura ningaruka nyinshi z'ingaruka zikomeye.
Meta-Isesengura ryerekana ko[7], ugereranije na B-Stream, umugezi birashoboka cyane ko twanduye Covid-19. Mu barwayi 143 banduye banduye, 74% banduye umugezi, naho 20% banduye b-umugezi. Gufatanya kwandura bishobora gutera indwara zikomeye zabarwayi, cyane cyane mumatsinda atishoboye nkabana.
Ubushakashatsi ku bana n'ingimbi biri munsi y'imyaka 18 bari mu bitaro cyangwa bapfuye bazize ibicurane mu gihe cy'ibicurane muri Amerika muri 2021-22 basanze[8]Ko ibintu byanduye byanduye hamwe na gripeza i Covid - 19 bikwiye kwitabwaho. Mu manza zijyanye no mu mutwe, 6% banduye Covidi - 19 na Drinepeza, naho igipimo cy'impfu ziterwa n'ibicurane zazamutse kuri 16%. Ibi bisobanuro byerekana ko abarwayi banduye Covid hamwe na Covid-19 na Drivereza bakeneye inkunga y'ubuhumekero kandi idakora ibirenze abo banduye ibicurane, kandi bagaragaza ko gufatanya ibyago by'indwara zikomeye mu bana .
2 Isuzuma ritandukanye rya Grippesa na Covid-19.
Indwara nshya kandi ibicurane byombi byanduye cyane, kandi hari bisa nkibimenyetso bimwe byamavuriro, nko guhiga, inkorora na miyalgia. Ariko, gahunda yo kuvura izi virusi zombi iratandukanye, kandi imiti igabanya ubukana ikoreshwa iratandukanye. Mugihe cyo kuvura, ibiyobyabwenge birashobora guhindura uburyo busanzwe bwindwara zindwara, bigatuma bigorana gusuzuma indwara kubimenyetso gusa. Kubwibyo, gusuzuma neza Covidi - 19 na Grigoza bigomba kwishingikiriza kuri virusi itandukaniro kugirango abarwayi bashobore guhabwamo kwivuza kandi neza.
Ibyifuzo byinshi byumvikanyweho no kwivuza byerekana ko kumenyekanisha virusi ya Covid-19 na Trieponza binyuze mu bizamini bya laboratoi ari ngombwa cyane mugutegura gahunda yumvikana.
"Gahunda y'ibihe n'ibicurane no kuvura (2020 Edition)"[9]na "Abakuze Ibicurane Ibicurane no kuvura Impuguke yinzobere yihutirwa (2022 Edition)"[10]Bose basobanura neza ko ibicurane bisa n'indwara zimwe na zimwe i Covid - 19, kandi Covid - imyaka yakorewe nk'umuriro, inkorora yumye kandi ituje gutandukanya ibicurane; Kwigaragaza cyane kandi bikabije umusomyi ukomeye, ubuhumekero bukabije, busa n'imikorere y'ibidukikije bigaragazwa n'ibicurane bikabije kandi binegura, kandi bigomba kugabanywa n'ibipimo.
"Urupapuro rwanduye rwanduye Dirogose na Gahunda yo kuvura (integuro ya cumi yo gushyira mu bikorwa urubanza"[11]yavuze ko kwandura Corvic-19 bigomba gutandukanywa na kantu yo hejuru yubuhumekero yatewe nindi virusi.
3 Itandukaniro ryo kuvura ibicurane na kabiri
2019-NCOV na Drimpleza ni indwara zitandukanye ziterwa na virusi zitandukanye, kandi uburyo bwo kuvura buratandukanye. Gukoresha neza imiti igabanya ubukana irashobora kubuza ingorane zikomeye nurupfu rwindwara zibiri.
Birasabwa gukoresha imiti mito mito ya molekile nka Nimatvir / Ritonavir, Azvune, Monola no kutabogama, Monola no kutabogama no kutabogama kurwanya ibiyobyabwenge nka Ambaviruzumab[12].
Ibiyobyabwenge byo kurwanya ibicurane bikoresha ahanini ababuza icumu (ORSACTIVIR, Zanamivir), Abigometse (Mabaglutinin abaramo (Mabaloxutin (Mabaloxtir abaramo (Mabaloxtir abaramo (Mabaloxase abaramo (Mabaloxavir), bafite ingaruka nziza kuri virusi izwi cyane[13].
Guhitamo gahunda ikwiye yo kurwanya ni ngombwa cyane kwivuza 2019-NCOV na Grippeza. Kubwibyo, ni ngombwa cyane kumenya pathogen neza kuyobora imiti yubuvuriro.
4 Covid-19 / Ibicurane A / Ibicurane B Igenzura rihuriweho na acide ya acide nucleic
Ibicuruzwa bitanga umusaruro wihuse kandi neza oF 2019-NCOV, Ibicurane A na Drigonza b virusi, kandi ifasha gutandukanya 2019-NCOV na Drinepoma, indwara ebyiri zandubira guhumeka hamwe nibimenyetso bisa nibimenyetso bitandukanye byo kuvura. Mu kumenya pathogen, irashobora kuyobora iterambere ryamavuriro rya gahunda zigamije kuvurwa no kwemeza ko abarwayi bashobora kubona ibintu bikwiye mugihe.
UMUTI WOSE:
Icyitegererezo Cyiza - Gukuramo Acide Nucleic - Kumenya Reagent - Polymeyese reaction
Kumenyekanisha neza: Menya Covidi-19 (Orf1ab, N), Ibicurane Arus virusi na virusi mibi muri tube imwe.
Twunvikana cyane: Lod ya Covidi-19 ni kopi 300 / ml, kandi iy grigoza a na b virusi 500 / ML.
Ubwishingizi Bwuzuye: Covid-19 ikubiyemo ibintu byose bizwi, hamwe na Grippeza A Kurwanya Igihembwe H1N1, H3N1, H1N1, HANC1, kugirango hatabaho gutahura.
Igenzura ryiza: Yubatswe-mubintu bibi / byiza, igenzura ryimbere na UDG enzyme Igenzura rine, kugenzura imbaraga nibikorwa kugirango tumenye ibisubizo nyabyo.
Byakoreshejwe cyane: Bihuye na Mainstream Umuyoboro wa kane-Umuyoboro wa PCR ku isoko.
Gukuramo byikora: Hamwe na Macro & micro-testSisitemu ya Acicction Nucleic ya acide no gukuramo reagenction, gukora akazi hamwe nibisubizo bitera imbere.
Amakuru yibicuruzwa
INGINGO
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2. Ibisobanuro byemewe _ liang Wannian: Igipimo cyimpfu muri Omirron ni inshuro 7 kugeza 8
3. Feng Lz, Feng S, Chen T, et al. Umutwaro w'ibicurane-bifitanye isano n'ibibazo by'ibicurane by'uburwayi mu Bushinwa, 2006-2015: ubushakashatsi bushingiye kubaturage [J]. Grippeza andi virusi ya respir, 2020, 14 (2): 162-172.
4. Li l, liu yn, wu p, et al. Impimbano zidasanzwe zishimishije mu Bushinwa, 2010-15: Kwiga abaturage [J]. Lancet UBUZIMA BWA BEMETS LAN9, 2019, 4 (9): E473-E481.
5. Iyabye MC, Russell CD, Harrison em, et al. SARS-COV-2 gufatanya virusi y'ibicurane, virusi yubuhumekero, cyangwa adenovirus. Lancet. 2022; 399 (10334): 1463-1464.
6. Yan X, Li K, Luo J, Wang q, Wei S. Ibyiciro bya Coinfection hagati ya SARS-COV-2 na Grippe Isubiramo na Meta-gusesengura. Int j. 2023; 136: 29-36.
7. Dao Tl, Holson P, Colson P, Miliyoni m, Gautrett P. Co-COV-2 na virusi ya Dleenza: Isubiramo rya sisitemu na Meta-Staces. J. Clin VIROL PLUS. 2021 Nzeri; 1 (3): 100036.
8. Adams K, Tastad KJ, huang s, et al. Ubwiyongere bwa SARS-COV-2 na Cleenza ibiranga ubuvuzi mu bana n'ingimbi bigeze mu zabukuru <imyaka 18 yari ibiganiro cyangwa yapfiriyemo ibicurane. Mmwr morb buntu buntu rep. 2022; 71 (50): 1589-1596.
9. Komite nziza yubuzima kandi nziza ya Repubulika y'Ubushinwa (PRC), ubuyobozi bwa Leta yubuvuzi gakondo bwubushinwa. Gahunda y'ibihe bibi na gahunda yo kuvura (2020 Edition) [j]. Ikinyamakuru cy'Ubushinwa indwara zandurira amavuriro, 2020, 13 (6): 401-405,411.
10. Ishami ryihutirwa ryabaganga ryishyirahamwe ry'ubuvuzi mu Bushinwa, ishami ry'ubuvuzi ryihutirwa ry'ishyirahamwe ry'ubuvuzi mu Bushinwa, Ishyirahamwe ry'ubuvuzi ryihutirwa ry'Ubushinwa, Ishyirahamwe ry'ubuvuzi ryihutirwa ry'Ubushinwa, Ishyirahamwe ry'ubuvuzi ryihutirwa, Komite ishinzwe ubushinwa. Ubwumvikane bwinzobere mu byihutirwa kubibazo byibicurane byabantu bakuru (2022 Edition) [j]. Ikinyamakuru cy'Ubushinwa cyo Kwitaho, 2022, 42 (12): 1013-1026.
11. Ibiro rusange bya komisiyo ishinzwe ubuzima na Kamere, ishami rikuru ry'ubuyobozi bwa Leta Ubuvuzi bw'Abashinwa. Reba ku icapiro no gukwirakwiza igitabo cyanduye (Gahunda yo kuvura (Ikigeragezo Icyiciro cya cumi).
12. Zhung Fujie, Zhuo Wang, Wang Quanhong, et al. Impuguke mu bwumvikane ku buvuzi bwo kurwanya avel coronavirus yanduye abantu [j]. Ikinyamakuru cy'Ubushinwa indwara zandurira mu bushinwa, 2023, 16 (1): 10-20.
. Ubwumvikane bwinzobere mu byihutirwa kubibazo byibicurane byabantu bakuru (2022 Edition) [j]. Ikinyamakuru cy'Ubushinwa cyo Kwitaho, 2022, 42 (12): 1013-1026.
Igihe cya nyuma: Werurwe-29-2024