RSV na HMPV: Igitabo cy’Ubuvuzi cyo Kumenya neza Abana

Isubiramo ryaImpapuro zubushakashatsi bwa kera

Virusi y'ubuhumekero (RSV) na Metapneumovirus ya muntu (HMPV) ni two bifitanye isano ya hafi na virusi muriPneumoviridaeumuryangoibyo bikunze kwitiranya ibibazo byindwara zubuhumekero zabana bato. Mu gihe ibiganiro byabo by’amavuriro byuzuzanya, amakuru y’ubushakashatsi (2016–2020) avuye mu bitaro 7 by’abana bo muri Amerika - birimo abarwayi 8.605 - agaragaza itandukaniro rikomeye ry’abaturage babo bafite ibyago byinshi, ubukana bw’indwara, ndetse n’ubuyobozi bw’amavuriro. Ubu bushakashatsi bwakoresheje igishushanyo mbonera, giteganijwe hamwe na sisitemu ya nasopharyngeal swab ikusanya no gupima virusi 8 zubuhumekero, itanga igereranya ryambere rinini, rigereranya nukuri kwisi kubaganga b'abana. Mu gusesengura ibipimo by’ibitaro, kwinjira muri ICU, gukoresha imashini ihumeka, no kumara igihe kinini mu bitaro (days3 iminsi), ishyiraho urufatiro rukomeye rw’indwara ya epidemiologiya mbere yo gutabara mu gihe cyo gukingira RSV nshya (urugero, inkingo z’ababyeyi, antibodiyite zimara igihe kirekire) kandi ikora urwego rwo guteza imbere urukingo rwa HMPV.

Gushakisha Urufunguzo 1: Itandukaniro Ryinshi-Risk

-RSV yibasira cyane cyane impinja:Ikigereranyo cyo hagati y'ibitaro cyari amezi 7 gusa, 29.2% by'abarwayi bemewe ni neonate (amezi 0-2). RSV nimpamvu nyamukuru itera ibitaro mubana bari munsi yamezi 6, ubukana bufitanye isano nimyaka.

-HMPV yibasira abana bakuru nabafite ibibazo:Ikigereranyo cyo hagati yo gushyirwa mubitaro cyari amezi 16, bigira ingaruka zikomeye kubana barengeje umwaka. Ikigaragara ni uko ubwinshi bw’indwara zishingiye ku buvuzi (urugero, umutima, imitsi, imitsi, ubuhumekero) bwikubye inshuro zirenga ebyiri abarwayi ba HMPV (26%) ugereranije n’abarwayi ba RSV (11%), bikagaragaza intege nke zabo.

Igicapo 1. Gukwirakwiza imyaka yo gusura ED no gushyirwa mubitarobifitanye isano na RSV cyangwa HMPV

mu bana bari munsi yimyaka 18.

Gushakisha Ibyingenzi 2: Gutandukanya Amavuriro Yerekana

-RSV igaragara hamwe nibimenyetso bigaragara byubuhumekero:Ifitanye isano cyane na bronchiolitis (76.7% byabarwayi bari mubitaro). Ibipimo byingenzi birimogukuramo urukuta rw'igituza (abarwayi 76.9%; 27.5% ED)natachypnea (abarwayi 91.8%; 69.8% ED), byombi bigaragara cyane kuruta muri HMPV.

-HMPV igaragaza umuriro mwinshi hamwe n'umusonga:Umusonga basuzumwe 35,6% by'abarwayi ba HMPV bari mu bitaro - bikubye kabiri RSV.Umuriro wari ikintu cyiganje cyane (abarwayi 83,6%; 81% ED). Mugihe ibimenyetso byubuhumekero nko gutontoma na tachypnea bibaho, muri rusange ntibikabije kurenza RSV.

Igishushanyo 2.Kugereranya ibiranga nubuvuziamasomoya RSV na HMPV mu bana bari munsi yimyaka 18.

Incamake: RSVahanini bitera indwara zikomeye ku bana bato, zirangwa nububabare bukomeye bwubuhumekero (kunuka, gusubira inyuma) na bronchiolitis.HMPVbikunze kwibasira abana bakuze bafite ibibazo, bagaragaza umuriro uvugwa, bigatera ibyago byinshi byo kurwara umusonga, kandi akenshi bitera igisubizo cyagutse cya sisitemu.

Gushakisha Ibyingenzi 3: Ibihe Byibihe Byingenzi

-RSV ifite impinga kare, iteganijwe:Ibikorwa byayo byibanda cyane, mubisanzwe bigera hagatiUgushyingo na Mutarama, kubigira virusi yibanze kubana bato mugihe cyizuba n'itumba.

-HMPV igera hejuru hamwe nibihinduka byinshi:Igihe cyacyo kigera nyuma, mubisanzwe hejuruWerurwe na Mata, kandi yerekana itandukaniro rikomeye umwaka-ku-mwaka no gutandukana kwakarere, akenshi bigaragara nk "umuraba wa kabiri" nyuma ya RSV igabanutse.

Igishushanyo 3.Muri rusange nurubuga rwihariye PCR positiveigipimo cya RSV na HMPV mubana bari munsi yimyaka 18 bafite ubwandu bukabije bwubuhumekero (ARI) -gusura ED hamwe no kubitaro.

Kwirinda no Kwitaho: Gahunda y'ibikorwa ishingiye ku bimenyetso

-Kurwanya RSV:Ingamba zo gukumira zirahari. Mu 2023, FDA yo muri Amerika yemeje antibody ikora igihe kirekire (Nirsevimab), ishobora kurinda impinja amezi 5 yambere. Byongeye kandi, urukingo rw'ababyeyi RSV rwimura neza antibodiyide zirinda impinja.

-Indwara ya HMPV:Kugeza ubu nta miti yemewe yo gukumira. Nyamara, abakandida benshi b'inkingo (urugero, urukingo rwa RSV / HMPV rwa AstraZeneca) bari mu bigeragezo byo kwa muganga. Ababyeyi barasabwa guhora bamenyeshwa amakuru agezweho ninzego zubuzima rusange.

Shakisha ubuvuzi bwihuse kuri buriwese muri "Ibendera ritukura":

-Umuriro mu mpinja:Ubushyuhe ≥38 ° C (100.4 ° F) ku mwana wese uri munsi y'amezi 3.

-Igipimo cyo guhumeka cyazamutse:Guhumeka birenze guhumeka 60 kumunota kubana 1-5, cyangwa guhumeka 40 kumunota kubana bafite imyaka 1-5, byerekana ibibazo byubuhumekero.

-Guhaza Oxygene Ntoya:Kwiyongera kwa Oxygene (SpO₂) biri munsi ya 90%, ikimenyetso gikomeye cyindwara zikomeye zagaragaye kuri 30% ya RSV na 32.1% by’indwara za HMPV ziri mu bitaro mu bushakashatsi.

-Ubunebwe cyangwa Kugaburira Ingorane:Ubunebwe bugaragara cyangwa kugabanuka kwamata kurenza kimwe cya gatatu mugihe cyamasaha 24, bishobora kuba intangiriro yo kubura umwuma.

Nubwo itandukanye muri epidemiologiya no kwerekana ivuriro, gutandukanya neza RSV na HMPV aho byitaweho bikomeje kuba ingorabahizi. Byongeye kandi, iterabwoba ry’amavuriro rirenze iyi virusi zombi, hamwe na virusi nka grippe A hamwe n’izindi ndwara ziterwa na virusi na bagiteri zihungabanya ubuzima bw’abaturage. Kwipimisha ku gihe kandi neza rero ni ingenzi cyane kubuyobozi bukwiye bwo gushyigikirwa, kwigunga neza, no gutanga ibikoresho bifatika

Kumenyekanisha AIO800 + 14-Pathogen Ikomatanyirijwe hamwe (Fluorescence PCR)(NMPA, CE, FDA, SFDA byemewe)

Kugira ngo iki cyifuzo gikemuke ,.Eudemon ™ AIO800 Sisitemu Yikora Nucleic Acide Sisitemu, Byahujwe na aIkibaho cyubuhumekero 14, itanga igisubizo gihindura - gutanga ukuri“Icyitegererezo, subiza”kwisuzumisha mu minota 30 gusa.

Ikizamini cyuzuye cyubuhumekeros virusi na bagiteriduhereye ku cyitegererezo kimwe, gifasha abatanga ubuvuzi bwambere gufata ibyemezo byokwizera, mugihe, kandi bigamije gufata ibyemezo.

Sisitemu Yingenzi Ibiranga Abakiriya bawe

 Byuzuye Byikora
Mugihe kitarenze iminota 5 amaboko ku gihe. Ntibikenewe abakozi ba molekile kabuhariwe.

- Ibisubizo byihuse
Igihe cyo guhinduranya iminota 30 gishyigikira ivuriro ryihutirwa.

- 14Indwara ya Pathogen
Kumenyekanisha icyarimwe:

Virusi:COVID-19, ibicurane A & B, RSV, Umujyanama, hMPV, Rhv, ubwoko bwa Parainfluenza I-IV, HBoV, EV, CoV

Indwara ya bagiteri:MP,Cpn, SP

-Lyofilized Reagents ihagaze ku bushyuhe bwicyumba (2–30 ° C)
Yoroshya kubika no gutwara, ikuraho ubukonje-urunigi.

Sisitemu yo kwirinda kwanduza
Ingamba 11 zo kurwanya umwanda zirimo UV sterilisation, kuyungurura HEPA, hamwe nakazi kafunze-karitsiye, nibindi.

Kumenyekanisha byihuse, byuzuye indwara ni ishingiro ryubuyobozi bugezweho bwo kwandura indwara zubuhumekero bwabana. Sisitemu ya AIO800, hamwe na automatike yuzuye, iminota 30, panel ya PCR igizwe, itanga igisubizo gifatika kumiterere yimbere. Mugushoboza kumenya hakiri kare kandi neza RSV, HMPV, nizindi ndwara zitera indwara, biha abaganga gufata ibyemezo byo kuvura bigamije, guhitamo ikoreshwa rya antibiyotike, no gushyira mu bikorwa uburyo bunoze bwo kurwanya indwara - amaherezo bikazamura ubuvuzi bwiza n’ubuzima bwiza.

#RSV #HMPV #Rapid #Kumenyekanisha #Respiratory #Patogene #Urugero-Gusubiza#MacroMicroTest