Kubera ko isuzuma rya aside nucleike rigenda riba ngombwa buri gihe, ese wigeze uhura n'izi mbogamizi: ibintu bishobora kwangirika mu gihe cyo gutwara, gufunguka bishobora kwanduza, cyangwa gutakaza ibikorwa bitewe no gukonjesha no gushonga kenshi?
Ikoranabuhanga rimaze ikinyejana rirwanya ikoreshwa ry’ikoranabuhanga—gukonjesha mu buryo bwa "vacuum friction"—ubu irimo gutera impinduka zikomeye mu nganda zipima molekile.
Uyu munsi, reka turebe uburyoMacroMicroTech (MMT)irimo guhangana n'ingingo enye zikomeye zibabaza hamwe n'ibyoikoreshwa rimwe, yumye neza kandi ikonjeshejwemikorosifeikoranabuhanga.
I. Kugaruka Gutangaje kw'Ikoranabuhanga Rimaze Ikinyejana: Amateka Magufi yo Kumisha Ibikoresho Bikonjeshejwe
Mu 1909, abahanga mu bya siyansi bakoresheje bwa mbere uburyo bwo gukonjesha mu gukonjesha kugira ngo babike serumu; mu 1919, byatumye habaho kubika ubwoko bwa virusi igihe kirekire. Byahoze bishimwa nk' "umurinzi w'imikorere y'ibinyabuzima," uburyo bwo gukonjesha mu gukonjesha ubu bwongeye kuvugurura kandi bukoreshwa cyane mu gusuzuma molekile muri iki gihe.
1. Urugendo Rurerure rw'Ibikoresho Bisanzwe by'Amazi
Kuva ku mukozi wakoze kugeza ku mukoresha wa nyuma, ibikoresho by’amazi bigomba kubikwa mu buryo bukonje mu gihe cyose cyo kubibika no gutwara. Gukoresha nabi akenshi bituma enzymes zangirika, kudakora neza kw’ibipimo, ndetse no kunanirwa gukora—ikibazo gikunze kugaragara mu mahugurwa no mu bushakashatsi bw’ingero.
2. Ubuzima bw'ibintu bihindura amazi mu kaga gakomeye
Iyo ifunguwe, agasanduku k'ibice bikonjeshejwe gakunze kubaho inshuro nyinshi zo gushonga, gukoreshwa no kongera gukonjeshwa—kugeza igihe byakoreshejwe cyangwa bigatabwa—bigatuma ibikorwa bitakaza agaciro n'imyanda.
Kumisha amazi mu buryo bukonjesha bikemura izi ngorane mu mizi. Mu gukura amazi mu mvange ku bushyuhe buke, enzymes na probes "birafungwa" mu buryo buhamye - ahanini bigahagarara igihe cyo kwangirika kugeza igihe bikoreshejwe.
II. Ibyiza bine by'ingenzi: Impamvu gukonjesha no kumisha ari igisubizo cyiza cyo gusuzuma molekile
Uduce duto twa MMT tw’amashanyarazi twumishijwe mu buryo bukonje kandi bukoreshwa rimwe gusa, twakozwe neza kugira ngo dukureho ingorane zikomeye z’inganda:
III. Iterambere ry'ikoranabuhanga: Kuki MMT yahisemo Micro-yumye ikoze muri frigoumubumbes?
Mu buryo butandukanye nko gukoresha lyophilization mu cyuma cyangwa PCR-tube, MMT yatangije uburyomikoro yumye ikoze muri firigoumubumbeimiterereibyo bigeraho intambwe eshatu z'ingenzi:
wowe"ImweMikorosife= Igisubizo kimwe cyuzuye”
Buri Microsphere ya 2 mm irimo ibice byose
—primers, enzymes, dNTPs—bigenzura neza kandi bigakuraho amakosa yo gusesengura.
woweIvugurura ry'Itegeko Nshinga ry'Umunota 1
Ibikoresho byihariye bituma imiyoboro mito ishobora gushonga vuba 50% kurusha imiterere isanzwe yumye mu buryo bwa fringe.
woweGuhuza imiterere ifunguye
Ikorana n'ibikoresho bitandukanye bikoreshwa (urugero: imiyoboro ya PCR ifite strip 8, imiterere ikoreshwa rimwe), ituma habaho koroherwa no koroherwa mu mikoreshereze.
IV. Ahazaza ni ubu: Uburyo Gukonjesha Bizahindura Uburyo bwo Gusuzuma Utunyangingo
Uko gusuzuma ingirabuzimafatizo bigenda byegereza aho abantu bavurirwa, gupima mu rugo, no kwita ku buzima bw'ibanze, MMT yiteguye ifite urubuga rwayo rukomeye rwo kumisha ibyuma muri firigo.
Urugero, mu igeragezwa ry’ibikoresho byo guhumeka, utubumbe tw’imirongo mito tw’ubukonje dutanga ibisubizo byizewe byoroshye, nta mugozi ukonje cyangwa imiterere igoye.
Amasezerano Asanzwe:
Kuri AIO800
Kuva"ihungabana ry'umunyururu ukonje"kuri"Ubushyuhe bw'icyumba butagira umupaka,"kuva"Ingamba zigoye"kuri"Gutahura intambwe imwe," Ikoranabuhanga ryo kumisha ibintu mu buryo bwo gukonjesha ririmo gusobanura neza imbibi z’ubwizerwe mu gusuzuma ibinyabutabire.
MMT izakomeza guhanga udushya mu nzira yo gutuza, gukora neza, koroshya no koroshya—itanga ubushobozi bwo gusuzuma neza kugira ngo itsinde inzitizi z'igihe n'aho iherereye.
Igihe cyo kohereza: Ukuboza-26-2025