Byuzuye-Byikora Byuzuye Icyitegererezo-Kuri-Igisubizo C. Gutahura Indwara Zitandukanye

Niki gitera C. Indwara itandukanye?

C. Indwara iterwa na bagiteri izwi nkaClostridioides diffile (C. diffile), ubusanzwe ibaho nta nkomyi mu mara. Nyamara, iyo igifu cya bagiteri ihungabanye, akenshi ikoreshwa rya antibiyotike yagutse, C. diffile irashobora gukura cyane kandi ikabyara uburozi, bigatera kwandura.

Iyi bagiteri ibaho muri yombiuburozinuburyo butari uburozi, ariko gusa uburozi bwa toxigenic (uburozi A na B) butera indwara. Zitera uburibwe mu guhagarika ingirabuzimafatizo zo mu nda. Uburozi A ni cyane cyane enterotoxine yangiza igifu, ikongerera ubushobozi, kandi ikurura ingirabuzimafatizo zirekura cytokine. Toxin B, cytotoxine ikomeye cyane, yibasira actin cytoskeleton yingirabuzimafatizo, biganisha ku kuzenguruka ingirabuzimafatizo, gutandukana, ndetse no gupfa. Hamwe na hamwe, ubwo burozi butera kwangirika kwinyama hamwe nubudahangarwa bukomeye bwumubiri, bugaragara nka colitis, impiswi, kandi mugihe gikomeye, colitis pseudomembranous colitis - gutwika gukabije kwinkondo y'umura.

NiguteC. Itandukanirogukwirakwira?

C.Diffe ikwirakwira byoroshye. Iraboneka mubitaro, bikunze kuboneka muri ICU, ku biganza by'abakozi b'ibitaro, hasi y'ibitaro no mu ntoki, kuri tometrometero ya elegitoroniki, n'ibindi bikoresho by'ubuvuzi ...

Ibintu bishobora gutera C. Kwandura

• ●Kujya mu bitaro igihe kirekire;

• ●Imiti igabanya ubukana;

• ●Imiti ya chimiotherapie;

• ●Kubaga vuba aha (amaboko ya gastric, bypass gastric, kubaga colon);

• ●Imirire ya Naso-gastric;

• ●Mbere C. kwandura;

Ibimenyetso bya C. Indwara itandukanye

C. kwandura kwandura birashobora kutoroha cyane. Abantu benshi bafite impiswi zikomeje no kutamererwa neza munda. Ibimenyetso bikunze kugaragara ni: impiswi, kubabara mu gifu, isesemi, kubura ubushake bwo kurya, umuriro.

Mugihe C. diff yanduye ikabije, hazabaho iterambere ryuburyo bugoye bwa C. diff izwi nka colitis, pseudomembranous enteritis ndetse nurupfu.

Gusuzumaya C. Kwandura

Umuco wa bagiteri:Yumva ariko itwara igihe (2-5days), ntishobora gutandukanya uburozi nuburozi;

Umuco w'uburozi:igaragaza ubwoko bwa toxigenic butera indwara ariko butwara igihe (3-5days) kandi ntibworoshye;

Kumenya GDH:byihuse (1-2hrs) kandi birahenze cyane, byoroshye cyane ariko ntibishobora gutandukanya uburozi nuburozi;

Akagari Cytotoxicity Kutabogama (CCNA): itahura uburozi A na B bufite sensibilité nyinshi ariko bitwara igihe (2-3days), kandi bisaba ibikoresho byihariye nabakozi bahuguwe;

Uburozi A / B ELISA: Ikizamini cyoroshye kandi cyihuse (1-2hrs) hamwe na sensibilité yo hasi hamwe nibibi bibi kenshi;

Ibizamini bya Nucleic Acide Amplification (NAATs): Byihuta (1-3h) kandi byoroshye cyane & byihariye, kumenya genes zishinzwe gukora uburozi ；

Byongeye kandi, ibizamini byo gufata amashusho kugirango bisuzume amara, nka CT scan na X-ray, birashobora kandi gukoreshwa mugufasha mugupima C. diff hamwe nibibazo bya C. diff, nka colitis.

Umuti wa C. Indwara itandukanye

Uburyo bwinshi bwo kuvura burahari kuriC. kwandura. Hano hari amahitamo meza ：

• ●Antibiyotike yo mu kanwa nka vancomycine, metronidazole cyangwa fidaxomicin ikoreshwa cyane kuko imiti ishobora kunyura muri sisitemu y'ibiryo kandi ikagera mu mara aho bagiteri ya C. ituye.

• ●Metronidazole yimitsi irashobora gukoreshwa mukuvura niba indwara ya C. diff ikabije.

• ●Guhindura mikorobe ya fecal byagaragaje akamaro ko kuvura indwara zanduye C. zitandukanye na C. diff zanduye zidakira antibiyotike.

• ●Kubaga birashobora gukenerwa kubibazo bikomeye.

Igisubizo cyo gusuzuma kuva MMT

Mu rwego rwo gukemura ikibazo cyihuse cya C. diffile, tumenyekanisha udushya twinshi twa Nucleic Acide Detection Kit ya Clostridium difficile toxin A / B, guha imbaraga inzobere mu buvuzi kwisuzumisha hakiri kare kandi neza no gushyigikira kurwanya indwara zanduye ibitaro.

图片链接：

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  ●Kumva neza: Kumenya hasi nka200 CFU / mL,;

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  ●Intego nyayo: Kugaragaza neza C. difficile toxine A / B gene, igabanya ibyiza byiza;

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  ●Kumenya Indwara ya Pathogen: Koresha ibipimo bya acide nucleic kugirango umenye neza genes z'uburozi, ushiraho igipimo cya zahabu mugupima.

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  ●Birahuye rwoseibikoresho nyamukuru bya PCR bivuga laboratoire nyinshi;

Icyitegererezo-Kuri-IgisubizoIgisubizo kuri Macro & Micro-Ikizamini cya AIO800 Mobile PCR Lab

 

• ●Icyitegererezo-Kuri-Gusubiza Automatisation - Fata umwimerere wicyitegererezo cyumwimerere (1.5-12 mL), ukuraho imiyoboro yintoki. Gukuramo, kwongera imbaraga, no gutahura byikora byuzuye, bigabanya igihe-cy-ikosa ryabantu.

• ●Kurinda ibyiciro umunani - Kurinda ibyerekezo byumuyaga, umuvuduko mubi, kuyungurura HEPA, guhagarika sterilisation, reaction zifunze, hamwe nubundi buryo bukomatanyije burinda abakozi kandi butanga ibisubizo byizewe mugihe cyo kwipimisha cyane.

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