Ibikoresho byo Gupima Carbapenemase Biciye ku Mutwe

CRE, igaragara hamwe naibyago byinshi byo kwandura, impfu nyinshi, ikiguzi kinini n'ingoranemu kuvura, asaba ko habahokuvumbura byihuse, neza kandi nezauburyo bwo gufasha mu gusuzuma no gucunga indwara.

Dukurikije ubushakashatsi bw’ibigo bikomeye n’ibitaro, Rapid Carbapenemases Detection Kit (Colloidal Gold) yo muri Macro & Micro -Test, ingana na multi-qPCR assay, itanga ukuri 100% mu kumenya carbapenemases mu dukoko twanduye. Iyi mikorere ihebuje irenze uburyo gakondo bwa phenotypic nka mCIM/eCIM na CDT. Icy'ingenzi ni uko ibizamini bya colloidal gold bigaragaza 100% by’ubuhanga, umwihariko, agaciro keza ko guhanura, n’agaciro kabi ko guhanura kuri buri carbapenemase yapimwe, bigaragaza imikorere yayo idasanzwe kandi ihoraho mu kumenya bagiteri zikora carbapenemase.

Amahitamo ya 1:

ByihuseAgakoresho ko Gupima Carbapenema (Colloidal Gold), intambwe igezweho yo gukemura ikibazo cyihutirwa cya CRE kibangamiye ubuzima rusange bw'isi, iminsi 1-2 mbere y'uko imiti ikoreshwa mu kuvura iyi ndwara ikwirakwira;

 Iminota 15gusa kugira ngo hamenyekane NDM, KPC, OXA-48, IMP na VIM mu isuzuma rimwe;

 Gukora byoroshye hakoreshejwe amazi yo gupima amaraso nta gupima plate, iminota 10 gusa yo gupima no gukaraba;

 Ubushobozi bwo kuvura indwara bwinshi kandi nta n'uburyo bwo kuvura indwara zisanzwe nka Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa cyangwa izindi ngero zikora β-lactamase;

 Uburyo bwo gukoresha ibintu mu buryo bwagutse: Ibintu bitandukanye birimo ibitaro, amavuriro, n'ibigo nderabuzima by'abaturage.

Amahitamo ya 2:

Agakoresho ko Gupima Ubudahangarwa bwa Carbapenem Gene (Fluorescence PCR), Ikizamini cya 6 muri 1hamwe n'umusaruro uri muriIminota 40, igaragaza nezaNDM, KPC, OXA23, OXA-48, IMP na VIMmu kizamini kimwe;

 Gufata ingero byoroshye: Amashono, agahu k'umura cyangwa amabere y'inkari;

 Ikiguzi cyagabanijwe: Intego 6 zabonetse mu kizamini kimwe gusa birinda ibizamini bidasubirwaho;

 Ubushobozi bwo kuvura no kugaragaza imiterere yihariye: 1000CFU/mL kugira ngo umuntu amenye uburyo bwo kuvura no kudahura n’izindi ndwara zitera indwara zo mu myanya y’ubuhumekero cyangwa ingero zirimo izindi jeni zidashobora imiti CTX, mecA, SME, SHV, TEM, nibindi;

 Guhuza neza: Ikoresheje ibikoresho bya PCR bisanzwe;