Gukumira no kugenzura kanseri mu buryo bwuzuye!

Buri mwaka ku itariki ya 17 Mata ni umunsi mpuzamahanga wahariwe kurwanya kanseri.

01 Incamake y'Icyorezo cya Kanseri ku Isi

Mu myaka ya vuba aha, bitewe n’ubwiyongere bw’ubuzima bw’abantu n’umuvuduko wo mu mutwe ukomeje kwiyongera, umubare w’abarwara ibibyimba na wo uriyongera uko umwaka utashye.

Kanseri mbi (kanseri) yabaye kimwe mu bibazo bikomeye by’ubuzima rusange bibangamiye ubuzima bw’abaturage b’Abashinwa. Dukurikije imibare iheruka, urupfu rw’ibibyimba bibi rungana na 23.91% by’impamvu zose zitera impfu mu baturage, kandi umubare w’ibibyimba bibi wakomeje kwiyongera mu myaka icumi ishize. Ariko kanseri ntisobanura "igihano cy’urupfu." Umuryango w’Abibumbye wita ku Buzima wagaragaje neza ko igihe cyose igaragaye hakiri kare, 60%-90% bya kanseri ishobora gukira! Kimwe cya gatatu cya kanseri gishobora kwirindwa, kimwe cya gatatu cya kanseri kiravurwa, kandi kimwe cya gatatu cya kanseri gishobora kuvurwa kugira ngo cyongere ubuzima.

02 Ikibyimba ni iki

Ikibyimba bivuga ikiremwa gishya cyaremwe no kwiyongera kw'uturemangingo tw'umubiri duto dukoresheje ibintu bitandukanye bitera kanseri. Ubushakashatsi bwagaragaje ko uturemangingo twa kanseri duhinduka mu buryo butandukanye n'uturemangingo dusanzwe. Muri icyo gihe, uturemangingo twa kanseri dushobora kwimenyereza impinduka mu buryo imibiri ihinduka binyuze mu guhinduranya glycolysis na oxidative phosphorylation.

03 Uburyo bwo kuvura kanseri ku giti cyabwo

Uburyo bwo kuvura kanseri bushingiye ku makuru ajyanye no gusuzuma indwara ziterwa n’uturemangingo ndetse n’ibyavuye mu bushakashatsi bw’ubuvuzi bushingiye ku bimenyetso. Butanga ishingiro ku barwayi kugira ngo bahabwe gahunda ikwiye yo kuvura, ikaba yarahindutse icyerekezo cy’iterambere ry’ubuvuzi bwa none. Ubushakashatsi bw’ubuvuzi bwemeje ko mu kubona impinduka mu turemangingo tw’uturemangingo, ubwoko bwa SNP mu turemangingo, imiterere ya gene n’imyitwarire ya poroteyine mu ngero z’ibinyabuzima z’abarwayi ba kanseri kugira ngo hamenyekane ingaruka z’imiti no gusuzuma imiterere y’indwara, no kuyobora uburyo bwo kuvura indwara ku giti cyabo, bishobora kunoza imikorere no kugabanya ingaruka mbi, kugira ngo hatezwe imbere ikoreshwa ry’ibikoresho by’ubuvuzi mu buryo bushyize mu gaciro.

Gupima kanseri hakoreshejwe molekile bishobora kugabanywamo ubwoko butatu bw'ingenzi: gusuzuma indwara, kubyara, no kuvura. Gupima indwara ni byo by'ingenzi mu byo bita "pathology therapeutic" cyangwa ubuvuzi bwihariye, kandi ubudahangarwa bw'umubiri bwinshi n'udukoko duto dushobora kwibasira utunyangingo tw'ingenzi twihariye ku ndwara ya kanseri n'inzira zo gutanga ibimenyetso bishobora gukoreshwa mu kuvura kanseri.

Uburyo bwo kuvura kanseri hifashishijwe molekile bugamije kwibasira molekile z’uturemangingo tw’uturemangingo kandi bukagira uruhare mu mikorere y’uturemangingo twa kanseri. Ingaruka zabyo zikunze kuba ku turemangingo tw’uturemangingo, ariko bigira ingaruka nke ku turemangingo dusanzwe. Ibikoresho byo kwakira imisemburo y’uburumbuke bw’uturemangingo, molekile zituma ibimenyetso bikwirakwira, poroteyine zikora ku ruhererekane rw’uturemangingo, ibigenzura apoptosis, enzymes za proteolytic, molekile zituma imitsi ikura, nibindi byose bishobora gukoreshwa nk’ibipimo bya molekile mu kuvura kanseri. Ku ya 28 Ukuboza 2020, "Ingamba z’Ubuyobozi zo Gukoresha Imiti Irwanya Indwara (Igeragezwa)" zashyizweho na Komisiyo y’Igihugu y’Ubuzima n’Ubuvuzi zagaragaje neza ko: Ku miti ifite ibipimo bya gene bisobanutse neza, ihame ryo kuyikoresha rigomba gukurikizwa nyuma yo gupima gene.

04 Gupima imiterere y'uturemangingo hifashishijwe ikibyimba

Hari ubwoko bwinshi bw'impinduka mu ngirabuzimafatizo mu tubyimba, kandi ubwoko butandukanye bw'impinduka mu ngirabuzimafatizo bukoresha imiti itandukanye. Gusobanura ubwoko bw'impinduka mu ngirabuzimafatizo no guhitamo neza imiti yihariye ni byo byonyine bituma abarwayi bungukira. Uburyo bwo gupima molekile bwakoreshejwe mu kumenya itandukaniro ry'utubyimba dufitanye isano n'imiti isanzwe ikoreshwa mu tubyimba. Dusesenguye ingaruka z'impinduka mu ngirabuzimafatizo ku mikorere y'imiti, dushobora gufasha abaganga gutegura gahunda ikwiye yo kuvura umuntu ku giti cye.

05 Igisubizo

Macro & Micro-Test yateguye urutonde rw'ibikoresho byo gupima imiterere y'uturemangingo tw'ibibyimba, bitanga igisubizo rusange ku buvuzi bwibanda ku bibyimba.

Agakoresho ko Gusuzuma Impinduka za Gene 29 z'Umuntu mu Gihe cy'Indwara (Fluorescence PCR)

Iyi kit ikoreshwa mu gupima mu buryo bw’umwimerere impinduka zisanzwe muri exons 18-21 za EGFR gene mu ngero z’abarwayi ba kanseri y’ibihaha batari abarwayi bato.

1. Sisitemu ishyiraho uburyo bwo kugenzura ubuziranenge bw'imbere, bushobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.

2. Ubuhanga bwo hejuru: Gutahura igisubizo cya aside nucleic reaction bishobora kugaragaza neza igipimo cy’impinduka cya 1% munsi y’ubwoko bwa 3ng/μL.

3. Ubwinshi buhanitse: Nta guhuza ADN y'umuntu yo mu bwoko bwa genome n'izindi nkomoko z'ibinyabuzima.

 

KRAS 8 Mutations Detection Kit (Fluorescence PCR)

Iyi kit igenewe gupima impinduka 8 muri kodoni 12 na 13 za gene ya K-ras muri ADN yakuwe mu bice by’indwara bya parafini y’umuntu.

1. Sisitemu ishyiraho uburyo bwo kugenzura ubuziranenge bw'imbere, bushobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.

2. Ubuhanga bwo hejuru: Gutahura igisubizo cya aside nucleic reaction bishobora kugaragaza neza igipimo cy’impinduka cya 1% munsi y’ubwoko bwa 3ng/μL.

3. Ubwinshi buhanitse: Nta guhuza ADN y'umuntu yo mu bwoko bwa genome n'izindi nkomoko z'ibinyabuzima.

 

Kit yo Gusuzuma Impinduka za Gene mu Mutation ya Human EML4-ALK (Fluorescence PCR)

Iyi kit ikoreshwa mu gupima ubwoko 12 bw'impinduka za EML4-ALK mu ngirabuzimafatizo z'abarwayi ba kanseri y'ibihaha batari bazima mu buryo bwa vitro.

1. Sisitemu ishyiraho uburyo bwo kugenzura ubuziranenge bw'imbere, bushobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.

2. Uburyo bworoshye bwo kumenya: Iyi kit ishobora kubona impinduka za fusion kugeza kuri kopi 20.

3. Ubwinshi buhanitse: Nta guhuza ADN y'umuntu yo mu bwoko bwa genome n'izindi nkomoko z'ibinyabuzima.

 

Kit yo Gusuzuma Impinduka za Gene ya ROS1 y'Umuntu (Fluorescence PCR)

Iyi kit ikoreshwa mu gupima ubwoko 14 bwa ROS1 fusion gene mutations mu bantu batari bazima.

1. Sisitemu ishyiraho uburyo bwo kugenzura ubuziranenge bw'imbere, bushobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.

2. Uburyo bworoshye bwo kumenya: Iyi kit ishobora kubona impinduka za fusion kugeza kuri kopi 20.

3. Ubwinshi buhanitse: Nta guhuza ADN y'umuntu yo mu bwoko bwa genome n'izindi nkomoko z'ibinyabuzima.

 

Kit yo Gusuzuma Impinduka mu Binyabuzima ya BRAF Gene V600E (Fluorescence PCR)

Iyi mashini ikoreshwa mu gupima mu buryo bw'ubuziranenge ikoreshwa mu gupima ihinduka rya gene V600E rya BRAF mu bice by'umubiri bya melanoma y'abantu, kanseri y'inkondo y'umura, kanseri ya tiroyide na kanseri y'ibihaha.

1. Sisitemu ishyiraho uburyo bwo kugenzura ubuziranenge bw'imbere, bushobora gukurikirana mu buryo bwuzuye inzira y'igerageza no kwemeza ubuziranenge bw'igerageza.

2. Ubuhanga bwo hejuru: Gutahura igisubizo cya aside nucleic reaction bishobora kugaragaza neza igipimo cy’impinduka cya 1% munsi y’ubwoko bwa 3ng/μL.

3. Ubwinshi buhanitse: Nta guhuza ADN y'umuntu yo mu bwoko bwa genome n'izindi nkomoko z'ibinyabuzima.

 

Nimero ya Kataloge	Izina ry'igicuruzwa	Ibisobanuro
HWTS-TM012A/B	Kit yo Gusuzuma Impinduka za Gene 29 z'Umuntu (Fluorescence PCR)	Ibipimo 16/agasanduku, ibizamini 32/agasanduku
HWTS-TM014A/B	KRAS 8 Mutations Detection Kit (Fluorescence PCR)	Ibipimo 24/agasanduku, ibizamini 48/agasanduku
HWTS-TM006A/B	Kit yo Gusuzuma Impinduka za Gene mu Mutation ya Human EML4-ALK (Fluorescence PCR)	Ibipimo 20/agasanduku, ibipimo 50/agasanduku
HWTS-TM009A/B	Kit yo Gusuzuma Impinduka za Gene ya ROS1 y'Umuntu (Fluorescence PCR)	Ibipimo 20/agasanduku, ibipimo 50/agasanduku
HWTS-TM007A/B	Kit yo Gusuzuma Impinduka za Gene V600E y'Umuntu (Fluorescence PCR)	Ibipimo 24/agasanduku, ibizamini 48/agasanduku
HWTS-GE010A	Kit yo Gusuzuma Impinduka za Gene ya BCR-ABL (Fluorescence PCR) y'umuntu	Ibizamini 24/agasanduku