Guhuza n'inama za ESCMID: Igisubizo cya IVDR-Certified NAAT POCT ku ndwara zo gupima Clostridioides zigoye

Clostridioides difficile ikomeje kuba imwe muimpamvu z'ingenzi zitera impiswi yandura iterwa n'ubuzimaku isi yose. Umutwaro uremereye cyane cyane ku barwayi bageze mu za bukuru, abantu bari mu bitaro, abatuye mu bigo bivuriramo igihe kirekire, ndetse n'abarwayi bahabwa imiti yica udukoko twinshi.

Nyamara gusuzuma indwara ya C. difficile (CDI) ni ikibazo kidasanzwe.

Bitandukanye n'izindi ndwara nyinshi zitera indwara zo mu gifu, C. difficile niindwara itera ibyagobishobora gutera indwara mu mara. Kutagira ibimenyetso bikunze kugaragara mu mavuriro, bivuze ko kuba hari ikinyabuzima gusa atari ngombwa ko bigaragaza ko gifite ubwandu.

Iri tandukaniro riri hagati yo gukoronizwa n'ubwandu riri mu nsanganyamatsiko y'isuzuma rya CDI rigezweho.

CDI ni iki?

Indwara ziterwa n'uburozi zitangira iyo ubwoko bw'uburozi bukora uburozi bwangiza uturemangingo tw'amara, bigatera ibimenyetso nka:

• · Impiswi idasobanutse
• · Ububabare bwo mu nda
• · Umuriro
• · Leukocytosis
• · Colitis

Dukurikije amabwiriza ya 2021 y’Umuryango w’Uburayi wita ku ndwara zandura (ESCMID), isuzuma rya laboratwari rigomba gukorwa cyane cyane ku barwayi bafite impiswi nyinshi zigaragaza indwara ya CDI.

Iri tegeko rigena impiswi nk'imyanya itatu cyangwa irenga idafite isuku mu masaha 24, kandi rishimangira ko ibyavuye muri laboratwari bigomba guhoragusobanurwa hamwe n'ibyerekanwa by'ubuvuzi.

Ibisubizo bya laboratwari bigaragaza ko ari byiza gusa ntibigomba kwihutishwa na CDI.

ESCMID: Guhuza Isuzumabumenyi ry'Ubuvuzi n'Isuzuma rya Laboratwari

Kugira ngo hongerwe uburyo bwo gusuzuma neza mu gihe hagabanywa uburyo bwo gusuzuma bukabije, ESCMID itanga inama yo gusuzuma mu ntambwe nyinshi.

Icyiciro cya mbere cyo gusuzuma gishobora gukoresha:

• · Glutamate dehydrogenase (GDH), cyangwa
• · Isuzuma ryo kongera aside ya nucleike (NAAT)

Ubwo buryo bwombi butanga uburyo bwo kumenya abarwayi bafite C. difficile mu buryo bworoshye.

Ugereranyije na GDH,NAAT itanga uburyo bwo kunoza imiterere yayo binyuze mu kumenya utunyangingo dufitanye isano n'uburozi twitwazwa n'ubwoko bw'uburoziaho kumenya gusa niba hari ikinyabuzima.

Ariko, ESCMID ivuga kandi ko kwishingikiriza kuri NAAT gusa bishobora gutuma umuntu afatwa n’indwara ikabije kuko utunyangingo tw’uburozi dushobora kugaragara mu bantu badafite ibimenyetso cyangwa abarwayi badafite indwara zijyanye n’uburwayi.

Kubera iyo mpamvu, ibisubizo byiza byo gusuzuma indwara bisobanurwa neza hamwe n'ibyavuye mu isuzuma ry'uburozi ndetse n'ibyavuye mu buvuzi.

Iyi ngamba ifasha gutandukanya:

• · CDI ikora
• · Guhinduka kw'abatishoboye mu buryo butari bwo
• · Kwandura mu gihe gito bisaba isuzuma ryinshi ry’ubuvuzi

Gushyigikira isuzuma rya CDI rijyanye n'amabwiriza

Mu rwego rwo gushyigikira laboratwari zishyira mu bikorwa isuzuma rya molekile mu nzira zo gusuzuma CDI, Macro & Micro-Test itanga uburyo bwo gusuzumaAgakoresho ko Gupima Aside Nucleic ka Clostridium difficile Toxin A/B Gene (Fluorescence PCR).

Isuzuma rigaragaza mu buryo butaziguyetcdAnatcdBjeni zikomoka kuriingero z'imyenge idafite ishusho, bigatuma hamenyekana vuba ubwoko bwa C. difficile butera uburozi.

Ibyiza by'ingenzi:

-Ububasha bwo kugaragaza ubukana bwinshi hamwe na LoD iri hasi nka: 200 CFU/mL/2.000 kopi/mL, bigatuma haboneka ubwoko bw’uburozi buri hasi mu buryo bwizewe.

-Kwibasira uburozi A (tcdA) n'uburozi B (tcdB) genes, isuzuma rigaragaza by'umwihariko ubwoko bushobora gutera ibintu by'ingenzi bitera ubukana bw'indwara ya CDI.

- Guhuza imikorere y’ikoranabuhanga mu buryo bworoshye: bihuye na porogaramu zisanzwe za PCR mu gihe nyacyo hamwe n’isuzuma ryikora ku buryo bwikora kuri Eudemon AIO 800

-Ifite icyemezo cya IVDR, igaragaza ko yujuje ibisabwa bikomeye n'amabwiriza agenga isuzuma ry'indwara mu mubiri w'i Burayi no gushyigikira laboratwari ku masoko yose y'i Burayi n'amahanga.

Gufasha gufata ibyemezo byiza by'ubuvuzi

Gusuzuma CDI neza bisaba ibirenze kumenya gusaC. bigoyeBisaba guhuza ibimenyetso by'ubuvuzi, ibyavuye muri laboratwari, no gusobanukirwa itandukaniro riri hagati yo gukwirakwira kw'indwara no kwandura.

Ihujwe n'inama za ESCMID, NAAT ifite ubushobozi bwo kugaragaza uburozi ifite uruhare runini mu kumenya uburoziC. bigoyeubwoko bw'indwara nk'igice cy'ingamba zirambuye zo gusuzuma CDI.

Binyuze mu bisubizo byayo byemewe na IVDR byo gupima molekile, Macro & Micro-Test yiyemeje gufasha laboratwari gutanga ibisubizo byihuse kandi byizewe bishyigikira ibyemezo by’ubuvuzi bifite ishingiro, ingamba zinoze zo kurwanya ubwandu, no kunoza umusaruro w’abarwayi.