15-Ubwoko bwa HR-HPV mRNA Kumenya - Kumenya Kubaho nigikorwa cya HR-HPV

Kanseri y'inkondo y'umura, intandaro y'impfu mu bagore ku isi, iterwa ahanini n'ubwandu bwa HPV. Ubushobozi bwa oncogenic bwanduye HR-HPV biterwa nubwiyongere bwimiterere ya gen E6 na E7. Intungamubiri za E6 na E7 zihuza poroteyine zo mu kibyimba p53 na pRb, kandi zigatera ikwirakwizwa ry'uturemangingo twa nyababyeyi.

Ariko, kwipimisha ADN ya HPV yemeza ko virusi ihari, ntabwo itandukanya hagati yanduye kandi yanduza cyane. Ibinyuranye na byo, gutahura inyandiko-mvugo ya HPV E6 / E7 mRNA ikora nk'ibimenyetso byihariye byerekana imiterere ya virusi ya oncogene ikora, bityo rero, ni ubuhanuzi bwuzuye bwerekana inkondo y'umura yitwa neoplasia (CIN) cyangwa kanseri itera.

HPV E6 / E7 mRNAkwipimisha bitanga inyungu zikomeye mukurinda kanseri y'inkondo y'umura:

• Isuzumabumenyi Ryukuri: Kumenya kwandura gukora, ibyago byinshi byanduye HPV, bitanga isuzuma risobanutse neza kuruta kwipimisha ADN ya HPV.
• Gutwara neza: Kuyobora abaganga mukumenya abarwayi bakeneye iperereza rindi, kugabanya inzira zidakenewe.
• Igikoresho gishobora Kugenzurwa: Gicurasi ishobora kuba igikoresho cyihariye cyo gusuzuma mugihe kizaza, cyane cyane kubantu bafite ibyago byinshi.
• Ubwoko 15 bwibyago byinshi byabantu Papillomavirus E6 / E7 Gene mRNA Detection Kit (Fluorescence PCR) kuva kuri #MMT, kumenya neza ibimenyetso byerekana indwara zishobora kwandura HR-HPV, nigikoresho cyingirakamaro mugupima HPV no / cyangwa gucunga abarwayi.

Ibiranga ibicuruzwa:

• Ubwishingizi bwuzuye: 15 HR-HPV ifitanye isano na kanseri y'inkondo y'umura itwikiriye;
• Ubwitonzi buhebuje: kopi 500 / mL;
• Umwihariko: Nta gikorwa cyambukiranya cytomegalovirus, HSV II na ADN genomic muntu;
• Ikiguzi-cyiza: Kwipimisha intego zifitanye isano cyane nindwara zishoboka, kugirango ugabanye ibizamini bitari ngombwa hamwe namafaranga yinyongera;
• Ubwiza buhebuje: IC kubikorwa byose;
• Ubwuzuzanye bwagutse: Hamwe na sisitemu nyamukuru ya PCR;