Impinduka mu mikorere ya PML-RARA mu bantu

Ishusho yagaragaye ku ihinduka rya PML-RARA y'abantu mu ngirabuzimafatizo

Ibisobanuro bigufi:

Iyi kit ikoreshwa mu gupima neza gene ya PML-RARA fusion mu magufwa y'abantu mu buryo bwa vitro.

Ohereza imeri kuri twe

Ibisobanuro birambuye ku gicuruzwa

Ibirango by'ibicuruzwa

Izina ry'igicuruzwa

HWTS-TM017AKit yo Gusuzuma Impinduka za Gene ya PML-RARA (Fluorescence PCR)

Ubumenyi bw'indwara

Leukemia itera indwara ya promyelocytic (APL) ni ubwoko bwihariye bwa leukemia itera indwara ya myeloid (AML). Hafi 95% by'abarwayi ba APL baherekezwa n'impinduka yihariye ya cytogenetike, ari yo t (15; 17) (q22; q21), ituma gene ya PML iri kuri chromosome 15 na gene ya retinoic acid receptor α (RARA) iri kuri chromosome 17 bihuzwa kugira ngo bikore gene ya PML-RARA fusion. Bitewe n'aho gene ya PML itandukaniye, gene ya PML-RARA fusion ishobora kugabanywamo ubwoko burebure (ubwoko bwa L), ubwoko bugufi (ubwoko bwa S) n'ubwoko butandukanye (ubwoko bwa V), bungana na 55%, 40% na 5%.

Umuyoboro

FAM	Ingirabuzimafatizo za PML-RARA
ROX	Igenzura ry'imbere

Ibipimo bya tekiniki

Ububiko	≤-18℃ Mu mwijima
Igihe cyo kumara	Amezi 9
Ubwoko bw'ingero	umusokoro w'amagufwa
CV	<5.0%
LoD	Kopi 1000/mL.
Ubwihariye	Nta buryo bwo guhuza imiterere y'uturemangingo twa BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, na TEL-AML1.
Ibikoresho Bikoreshwa	Sisitemu ya PCR ikoreshwa mu gihe nyacyo ya 7500 Sisitemu za PCR zikoreshwa mu buryo bwihuse 7500 QuantStudio^®Sisitemu 5 za PCR mu gihe nyacyo Sisitemu za PCR za SLAN-96P mu gihe nyacyo (Hongshi Medical Technology Co., Ltd.) LightCycler^®Sisitemu ya PCR ya 480 mu gihe nyacyo Sisitemu yo Gupima PCR ya LineGene 9600 Plus mu gihe nyacyo (FQD-96A, ikoranabuhanga rya Hangzhou Bioer) MA-6000 Real-Time Quantitative Thermocycler (Suzhou Molarray Co., Ltd.) Sisitemu ya BioRad CFX96 ya PCR mu gihe nyacyo Sisitemu ya BioRad CFX Opus 96 ya PCR mu gihe nyacyo