Clostridium Difuji Glutamate Yumurwatsi (GDH) na Toxin A / B.

Clostridium Difficile (CD) niyo igategeka Grami-nziza ya Anaerobic, ni flora isanzwe mumubiri wumuntu. Ibindi bilora bizabuzwa kugwira kubera antibiyotike ikoreshwa mubipimo binini, na cd yororoka mumubiri wumuntu ku bwinshi. CD igabanijwemo toxin-gukora ibintu bitarenze ubwoko. Ubwoko bwa CD butanga Glutamate dehydrownase (GDH) iyo bororoka, kandi imigenzo ya toxigenic gusa ni pathogenic. Guhinduranya kwa toxin birashobora kubyara toxine ebyiri, A na B. toxin a ni enterotoxine, ikaba irohama urukuta rwumuraro, uruzinduko rwakagari, rwiyongereyeho urukuta rwinyama, kuva amaraso. Toxin B ni cytotoxine, yangiza cytoskeleton, itera Cyknose ya selile na necrosis, kandi yangiza ingirabuzimafatizo zo mu nda, bituma impisizi yo mu nda, bikaviramo impiswi na pseudoomembanous colilitis.