Carbapenemase

Ibisobanuro bigufi:

Iki gikoresho gikoreshwa mugushakisha ubuziranenge bwa NDM, KPC, OXA-48, IMP na VIM karbapenemase ikorerwa mu ngero za bagiteri zabonetse nyuma yumuco muri vitro.


Ibicuruzwa birambuye

Ibicuruzwa

Izina RY'IGICURUZWA

HWTS-OT085E / F / G / H -Ibikoresho byo Kumenyekanisha Carbapenemase (Zahabu ya Colloidal)

Epidemiologiya

Antibiyotike ya Carbapenem ntisanzwe ant-antibiyotike ya lactam hamwe na antibacterial nini yagutse hamwe nibikorwa bikomeye bya antibacterial[1].Kubera ituze kuri β-lactamase n'uburozi buke, yabaye imwe mu miti ikomeye ya antibacterial yo kuvura indwara ziterwa na bagiteri.Carbapenem irahagaze neza kuri plasmid-yunganirwa-yagutse-ya-lactamase (ESBLs), chromosomes na plasmid-yunganirwa na cephalosporinase (enzymes ya AmpC)[2].

Ibipimo bya tekiniki

Intego y'akarere NDM, KPC, OXA-48, IMP na VIM karbapenemase
Ubushyuhe bwo kubika 4 ℃ -30 ℃
Ubwoko bw'icyitegererezo Ingero za bagiteri zabonetse nyuma yumuco
Ubuzima bwa Shelf Amezi 24
Ibikoresho bifasha Ntabwo bisabwa
Ibikoreshwa birenze Ntabwo bisabwa
Igihe cyo kumenya Ingero za bagiteri zabonetse nyuma yumuco
LoD

Ubwoko bwa NDM:0.15ng / mL

Ubwoko bwa KPC: 0.4ng / mL

Ubwoko bwa OXA-48:0.1ng / mL

Ubwoko bwa IMP:0.2ng / mL

Ubwoko bwa VIM:0.3ng / mL.

Ingaruka Kuri NDM, KPC, OXA-48 ubwoko bwa karbapenemase, nta ngaruka zifatika ziboneka murwego rwa 100ng / mL;kuri IMP, ubwoko bwa VIM karbapenemase, nta ngaruka zifatika ziboneka murwego rwa 1μg / mL.

Urujya n'uruza rw'akazi

Ibikoresho byo gutahura Carbapenemase (Uburyo bwa zahabu ya Colloidal) -04

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